Van de Ven Double Ends The Toffees' Run at Brand New Home Ground
Micky van de Ven emerged as the initial backline player to net twice in a English top-flight game for Tottenham since the Belgian defender in March 2013.
Match summary
The Spurs defender nods home twice in first half
The home side's defender has goal ruled after video check
Pape Matar Sarr nets final goal in 89th minute
This loss is Everton's first at their new ground
Micky van de Ven scored twice as Spurs prolonged their winning streak in away games in the Premier League and delivered Everton their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed Goodison Park behind after 133 years at the end of last season.
But Tottenham's leader Van de Ven pounced twice from set-pieces in the first half to place their strong form at jeopardy, and they were failed to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - nodded in a third to seal the victory.
The Everton defender thought he had levelled the tally five minutes after Van de Ven's first goal, directing a bullet header past Guglielmo Vicario from an set-piece.
The Portuguese striker, in the meantime, missed a handful of chances, while Vicario made a succession of fine saves to ensure the London club went five away games unbeaten in the Premier League.
But the video assistant referee stepped in, advising Craig Pawson to check the score on the pitchside monitor and the referee ruled that the winger and Iliman Ndiaye were in offside positions and had interfered with the Tottenham goalkeeper.
This victory moves the manager's team up to third in the Premier League, a handful of points off local foes and leaders Arsenal.
Everton stay in 14th position and are six points ahead of the relegation zone.
Spurs breakdown: The defender excels in role at each end of the field
Following a uninspiring weekday display in the Champions League against Monaco, where they managed a mere two shots on target, Frank chose the French striker in attack instead of former Toffees player the Brazilian.
The summer signing was unable to make much of an impact before being substituted for Richarlison after an hour on the pitch, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an offensive threat to be reckoned with.
Tottenham's opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball back across the six-yard box for an unmarked Van de Ven to score.
And Ven de Ven - filling in as skipper in Cristian Romero's unavailability - added his next goal in first-half stoppage time as he rose above Jordan Pickford to head home.
Van de Ven was just as outstanding in defence, partnering effectively with Kevin Danso as the duo handled excellently with the numerous deliveries sent their way by Everton.
Toffees breakdown: Everton lacking finishing touch
Everton's recent stadium had been a happy hunting ground, but it appears the freshness may have worn off slightly and fans flocked to the exits after the midfielder's final goal for Tottenham.
The break in Everton's unbeaten home run won't be a major worry for the manager, but their striker situation are.
Beto and Thierno Barry - the Everton's pair of established centre-forwards - had scored just a single goal between them before the weekend's match.
And they were failed to add to that poor tally on a damp and dreary night on Merseyside.
The striker's form was epitomized when he chose to overhead kick a clear chance from close range, despite having room and time to reposition for a simpler attempt that would have challenged Vicario.
The substitute, too, was unable to make an impact after coming on for the starter in the 65th minute.
It was not for a shortage of opportunity. Most of Everton's offensive moves came through the winger and the forward, who tirelessly whipped threatening crosses into the Spurs penalty area.
Upcoming fixtures for these two sides?
The Toffees: The team head to Sunderland in the Premier League on early November at 20:00 GMT.
Tottenham: Spurs travel to Newcastle's ground on late October for their next round Carabao Cup match against the Magpies.